T Cell Regulatory Balance

Spatial Proteomics
Patient Stratification
Oncology
Immunology
Overview

Immune cells play a crucial role in recognizing and eliminating foreign pathogens within the body and maintaining homeostatic conditions. In recent years, therapeutic approaches aimed at modulating immune cell function have become pivotal in treating inflammatory diseases and cancer. Notably, immune checkpoint inhibitors, such as anti-PD1 therapies, prevent the deactivation of disease-fighting immune cells.

This insight report focuses on characterizing exhausted and regulatory T cells, examining their spatial localization and cellular interactions within the tissue microenvironment.

Key Questions Answered
Are exhausted and regulatory T cells present in my samples?
Outputs
  1. Quantification of exhausted and regulatory T cell abundance
  2. Quantification of cellular and spatial features, including cell type frequency, cell-cell interactions, and cell neighborhoods in the context of functional T cells
Deliverables
Insights Report
ECP Visualizer
ECP Explorer
Image(s)
Data Plot(s)
Data Table(s)
CSV File(s)